Start with something designed around a graphical interface, pretty much anything based on Ubuntu will do this (Linux Mint, Zorin, Pop!_OS, etc).
If you use Nvidia Pop!_OS has an ISO file with Nvidia drivers already installed. It isn’t hard to get Nvidia drivers on other distros but the more done for you the better.
Pretty much any distro will do, but Ubuntu-based ones tend to be easier to use due to having menus and buttons for most everything. As for apps, here are my suggestions
3D
Blender
DAW
Ardour
LMMS
Bitwig
~VIDEO EDITING~
Davinci Resolve (if on Nvidia)
Kdenlive
Olive (alpha software, be wary of crashes and save often)
IMAGES
GIMP
Krita
Photopea (web app)
Lights may be possible with OpenRGB but I haven’t personally messed with these kinda of software